Agar Scientific

Microscopy and Lab
supplies at your fingertips

NLS Vibrating Blade Tissue Micro-Slicer


High performance, vibrating blade tissue micro-slicer.

All prices exclude VAT.

NLS-MT and NLS-AT are high performance, vibrating blade tissue micro-slicers capable of producing highly accurate and consistent sections. NLS can section fresh and living tissue without the need to either freeze or paraffin embed specimens, unlike other types of microtomes which require hardened or frozen tissue.


  • Integral vibration isolation stage
  • Auto retraction function - prevents the blade from touching the specimen surface during backward movement
  • Detachable blade holder
  • Detachable ice bath
  • Frequency digital display

The vibrating blade is powered by a high quality linear motor which minimises chatter (irregular vertical vibration) to typically 1 micron at the optimum resonance point. The vibration frequency is adjustable between 50 to 100Hz and the frequency displayed, which allows the blade to reach the minimum resonance point for the specific working conditions and for the specific sample. The vibration amplitude is continuously adjustable from 0 to 2mm and the cutting speed continuously adjustable from 0 to 44mm/min. These three functions can be independently set allowing full control to produce optimum slices.

The ability to section soft tissues has clear advantages:

  • Less chance of artefacts caused by paraffin embedding or freezing
  • Does not fracture cell membranes
  • No need to de-paraffinise and rehydrate sections prior to immunostaining
  • No high temperatures or harsh chemical treatments
  • No special microtome blades required

With conventional tissue slicers, it can be difficult to obtain high quality tissue sections as these instruments often show irregular vertical blade vibration and significant loss of performance after long-term use. The NLS has overcome these challenges by incorporating a linear motor designed for long-term use without deterioration of performance.

The slicer is easy to use and setup, producing high quality sections with minimal damage to tissues and cells.

Two models are available:
NLS-MT - with manual thickness operation
NLS-AT - sections automatically by programmable options

Range of application

  • Neuroscience
  • Neurochemistry
  • Histochemistry
  • Cytochemistry
  • Physiology
  • Pharmacology
  • Toxicology
  • Pharmacokinetics
  • Enzyme cytochemistry
  • Histopathology
  • Botany
  • Applied entomology
  • Regenerative medicine
  • Tissue engineering
  • Tissue culture
  • Other research areas using tissue sections

Book a Demo!
We can arrange personal demonstrations of this equipment in our dedicated demonstration lab at Stansted, or at your own premises.  Click here to find out more >>

Models NLS-MT: Manual Model
  NLS-AT: Automatic Model
Dimensions W345mm x D500mm x H240mm
Weight 35kg
Power 100V 2A 50/50Hz
(Inverter required for 240V operation)
Blade reciprocation frequency 50-100Hz
Blade reciprocation amplitude 0-2mm
Abnormal vibration Maximum 2μm (regularly less than 1μm)
Blade advance speed 0-44mm/min
Blade retraction speed 71mm/min
Limit of the specimen(s) size for sectioning W30 x D25mm
Vertical movement width of specimen stage 15mm

  NLS Micro-Slicer Datasheet

Description Code Stock Unit Price Qty
NLS-MT vibrating blade micro-slicer - manual AGB4001 Out of stock EA
NLS-AT vibrating blade micro-slicer - automatic AGB4002 Out of stock EA

NLS vibrating blade tissue micro-slicer

  • NLS vibrating blade tissue micro-slicer
  • NLS vibrating blade tissue micro-slicer
  • NLS vibrating blade tissue micro-slicer
  • NLS vibrating blade tissue micro-slicer
  • NLS vibrating blade tissue micro-slicer
  • NLS vibrating blade tissue micro-slicer