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quantifoil

UltrAuFoil Holey Gold Films

UltrAuFoil® - ultra-stable gold supports for electron cryomicroscopy.

All prices exclude VAT.
Name & Code
Grouped product items
Code & DescriptionAvailabilityPriceQty
AGS188-1
UltrAuFoil R2/1 on 200 mesh Gold (Pk of 10)
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POA
POA
AGS188-2
UltrAuFoil R2/2 on 200 mesh Gold (Pk of 10)
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POA
POA
AGS187-3
UltrAuFoil R1.2/1.3 on 300 mesh Gold (Pk of 10)
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POA
POA
AGS189-3
UltrAuFoil R0.6/1 on 300 mesh Gold (Pk of 10)
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POA
POA
Product Description

These recently developed ultra-stable gold supports for electron cryomicroscopy reduce the movement of frozen specimens during imaging. This improves image contrast and quality leading to better 3D reconstruction in TEM tomography applications.

During imaging at cryo-temperatures, traditional carbon supports move, particularly at the beginning of irradiation. This movement blurs images and makes it difficult to determine the structures of small and challenging molecules

Characteristics of UltrAuFoil®

  • Thickness of gold foil: approx 500Å
  • Structure of gold foil: regular square array of micrometer-sized circular holes
  • Geometry: R1.2/1.3 R0.6/1 and R2/2
  • Gold 300 mesh (R0.6/1 or R1.2/1.3 geometry)
  • Gold 200 mesh (R2/2 geometry)
  • Other types are also available

Using UltrAuFoils®, designed at MRC's Laboratory of Molecular Biology by Dr Christopher J Russo and Dr Lori A Passmore and produced by Quantifoil Micro Tools, specimen motion can be reduced significantly.


Refs:
Russo, CJ & Passmore, LA (2014). Ultrastable gold substrates for electron cryomicroscopy. Science. 346 (6215) pp. 1377-1380.
Bharat, TA, Russo, CJ, Leo, J. Passmore, LA & Scheres, SH (2015). Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to sub-tomogram averaging. Structure. 23 (9) pp. 1743-1753.

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